Yau Ppy, Dhand N K, Thomson P C, Taylor R M
Faculty of Veterinary Science, University of Sydney, New South Wales, Australia.
Aust Vet J. 2017 May;95(5):149-155. doi: 10.1111/avj.12576.
To identify risk factors for canine lymphoma in dogs from New South Wales, Australia, and to compare factors affecting remission duration.
Client-owned dogs diagnosed with lymphoma presented to the University Veterinary Teaching Hospital (UVTH), University of Sydney, between 2001 and 2009 (n = 134) were compared with a control population of dogs seen in that period of time with a diagnosis other than lymphoma to evaluate association of explanatory variables (breed, age and sex) with the outcome (case or control status).
The Australian Cattle Dog (odds ratio (OR) = 4.71; 95% confidence interval (Cl) 2.31-9.62; P < 0.001), Doberman (OR = 7.64; 95% Cl 2.87-20.34; P = 0.001) and Rottweiler (OR = 4.52; 95% Cl 2.09-9.73; P = 0.001) had increased odds of lymphoma among dogs attending the UVTH compared with crossbreds. The results suggested that the Border Collie (OR = 3.38; 95% Cl 1.52-7.53; P = 0.008) and Boxer (OR = 3.85; 95% Cl 1.65-8.95; P = 0.006) also have increased odds of lymphoma among the pure-breed dogs attending the UVTH when compared with crossbred dogs.
The results of this study confirmed a breed predilection for lymphoma in dogs, with the Australian Cattle Dog and Doberman having increased odds of lymphoma.
确定澳大利亚新南威尔士州犬类淋巴瘤的风险因素，并比较影响缓解期的因素。
将2001年至2009年间就诊于悉尼大学兽医教学医院（UVTH）且被诊断为淋巴瘤的客户自有的犬只（n = 134）与同期就诊的诊断为非淋巴瘤的对照犬只群体进行比较，以评估解释变量（品种、年龄和性别）与结果（病例或对照状态）之间的关联。
与杂种犬相比，就诊于UVTH的澳大利亚牧牛犬（优势比（OR）= 4.71；95%置信区间（Cl）2.31 - 9.62；P < 0.001）、杜宾犬（OR = 7.64；95% Cl 2.87 - 20.34；P = 0.001）和罗威纳犬（OR = 4.52；95% Cl 2.09 - 9.73；P = 0.001）患淋巴瘤的几率增加。结果表明，与杂种犬相比，就诊于UVTH的纯种犬中边境牧羊犬（OR = 3.38；95% Cl 1.52 - 7.53；P = 0.008）和拳师犬（OR = 3.85；95% Cl 1.65 - 8.95；P = 0.006）患淋巴瘤的几率也增加。
本研究结果证实犬类淋巴瘤存在品种易感性，澳大利亚牧牛犬和杜宾犬患淋巴瘤的几率增加。
