Tian Hao, Xu Yiren, Liu Shaojin, Jin Dingsha, Zhang Jianjun, Duan Liusheng, Tan Weiming
Engineering Research Centre of Plant Growth Regulators, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China.
Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.
Molecules. 2017 Apr 26;22(5):694. doi: 10.3390/molecules22050694.
A series of novel C-3-OH substituted gibberellin derivatives bearing an amide group were designed and synthesized from the natural product gibberellic acid (GA₃). Their activities on the plant growth regulation of rice and were evaluated in vivo. Among these compounds, and exhibited appreciable inhibitory activities on rice (48.6% at 100 μmol/L) and (41.4% at 100 μmol/L), respectively. These results provide new insights into the design and synthesis of potential plant growth regulators.
从天然产物赤霉酸（GA₃）设计并合成了一系列带有酰胺基团的新型C-3-OH取代赤霉素衍生物。对它们在水稻上的植物生长调节活性进行了体内评价。在这些化合物中，[具体化合物1]和[具体化合物2]分别对水稻（100 μmol/L时抑制率为48.6%）和[另一植物名称]（100 μmol/L时抑制率为41.4%）表现出明显的抑制活性。这些结果为潜在植物生长调节剂的设计与合成提供了新的见解。
