Zhang Xiao-Ping, Xia Zu-Yao, Chen Bao-An, Gao Chong
Department of Hematology and Oncology, Zhongda Hospital,Medical School, Southeast University, Nanjing,210009, Jiangsu Province, China.
Department of Hematology and Oncology, Zhongda Hospital,Medical School, Southeast University, Nanjing,210009, Jiangsu Province, China. E-mail:
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017 Apr;25(2):613-616. doi: 10.7534/j.issn.1009-2137.2017.02.056.
Myeloma nephropathy is a common complication in patients with myltiple myeloma (MM) that causes high morbidity. In the majority of cases, renal impairment is caused by the accumulation and precipitation of light chains, which form casts in the distal tubules, resulting in renal obstruction. This review discusses the recent advances on its treatment, so as to provide reference for clinical treatment of MM induced-renal failure.
骨髓瘤肾病是多发性骨髓瘤（MM）患者常见的并发症，发病率很高。在大多数情况下，肾功能损害是由轻链的积聚和沉淀引起的，轻链在远端肾小管中形成管型，导致肾梗阻。本文综述了其治疗的最新进展，为MM所致肾衰竭的临床治疗提供参考。
