Kannan Karthiga, Alwithanani Naif, Salama Mohamed, Kumar Manoj, Uthappa Roshan, Ahamed Mazood
Department of Oral Medicine & Radiology, College of Dentistry, Majmaah University, Saudi Arabia.
Department of Periodontics, College of Dentistry, Majmaah University, Saudi Arabia.
Ethiop J Health Sci. 2016 Sep;26(5):487-490. doi: 10.4314/ejhs.v26i5.11.
Eosinophilic granuloma (EG), one of the three clinical forms of Langerhans cell histiocytosis (LCH), is a benign inflammatory reaction to an unknown etiologic agent. It most commonly occurs in children and young adults. The most frequently involved bones are the skull, the ribs and the femurs. Alongside the cranium, the maxilla and mandible can also be affected.
Herein, we report a case of eosinophilic granuloma in a ten years old boy involving posterior quadrants upper and lower jaws as a destructive lesion involving gingiva, periodontium and alveolar bone. Involvement of other bones is ruled out by nucleotide imaging study.
EG should be considered as a differential diagnosis whenever there is a bony destructive lesion involving alveolar bone of the Jaws. Early diagnosis and surgical intervention will resolve the lesion.
嗜酸性肉芽肿(EG)是朗格汉斯细胞组织细胞增多症(LCH)的三种临床形式之一,是对未知病因的良性炎症反应。它最常见于儿童和年轻人。最常受累的骨骼是颅骨、肋骨和股骨。除颅骨外,上颌骨和下颌骨也可受累。
在此,我们报告一例10岁男孩的嗜酸性肉芽肿,累及上下颌后象限,表现为累及牙龈、牙周膜和牙槽骨的破坏性病变。核苷酸成像研究排除了其他骨骼受累。
当出现累及颌骨牙槽骨的骨质破坏性病变时,应将EG视为鉴别诊断之一。早期诊断和手术干预可使病变得到解决。