利用表观扩散系数评估类风湿关节炎早期的滑膜炎和骨侵蚀
Assessing Synovitis and Bone Erosion With Apparent Diffusion Coefficient in Early Stage of Rheumatoid Arthritis.
作者信息
Qu Jin, Lei Xinwei, Zhan Ying, Li Huixia, Zhang Yu
机构信息
From the *Tianjin First Center Hospital, Tianjin; and †Philips Healthcare, Beijing, China.
出版信息
J Comput Assist Tomogr. 2017 Sep/Oct;41(5):833-838. doi: 10.1097/RCT.0000000000000609.
PURPOSE
The aim of this study was to assess the value of apparent diffusion coefficient (ADC) in distinguishing synovitis from joint fluid and bone erosion from cysts.
METHODS
Twenty-eight patients with suspected rheumatoid arthritis underwent diffusion-weighted imaging and pre- and post-contrast-enhanced magnetic resonance imaging. The mean ADC values were compared between synovitis and joint effusion and between bone erosion and cyst.
RESULTS
Mean ADC value of synovitis was significantly lower than that of the joint effusion (2.6 ± 0.37 × 10 vs 1.63 ± 0.37 × 10 mm/s, P < 0.001; cutoff value 2.10 × 10 mm/s). Mean ADC value of bone erosion was significantly lower than that of the cysts (1.61 ± 0.39 × 10 vs 2.39 ± 0.34 × 10 mm/s, P < 0.001; cutoff value 2.04 × 10 mm/s).
CONCLUSION
Apparent diffusion coefficient can be used in differentiating between synovitis and joint effusion and between bone erosion and cysts.
目的
本研究旨在评估表观扩散系数（ADC）在区分滑膜炎与关节液以及骨侵蚀与囊肿方面的价值。
方法
28例疑似类风湿关节炎患者接受了扩散加权成像以及对比增强前后的磁共振成像检查。比较了滑膜炎与关节积液之间以及骨侵蚀与囊肿之间的平均ADC值。
结果
滑膜炎的平均ADC值显著低于关节积液（2.6±0.37×10对1.63±0.37×10mm²/s，P<0.001；临界值2.10×10mm²/s）。骨侵蚀的平均ADC值显著低于囊肿（1.61±0.39×10对2.39±0.34×10mm²/s，P<0.001；临界值2.04×10mm²/s）。
结论
表观扩散系数可用于区分滑膜炎与关节积液以及骨侵蚀与囊肿。
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