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巨细胞病毒性前葡萄膜炎继发于局部应用环孢素 A 之后。

Cytomegalovirus Anterior Uveitis Following Topical Cyclosporine A.

机构信息

a Ocular Inflammation and Immunology Service , Singapore National Eye Centre , Singapore.

b Ocular Inflammation and Immunology Research Group, Singapore Eye Research Institute , Singapore.

出版信息

Ocul Immunol Inflamm. 2018;26(1):90-93. doi: 10.1080/09273948.2017.1306083. Epub 2017 Apr 27.

Abstract

Cytomegalovirus (CMV) anterior uveitis and endotheliitis occurs among immunocompetent individuals and may manifest as Posner-Schlossman syndrome or Fuchs uveitis syndrome. The condition may first present following ophthalmic surgery, the use of a fluocinolone-sustained steroid drug delivery implant, or the use of topical prostaglandin analogues for the treatment of glaucoma. We report the first case of a non-human immunodeficiency virus-infected individual who presented with CMV anterior uveitis after the use of topical cyclosporine A 0.05% ophthalmic emulsion for the treatment of symptomatic dry eyes.

摘要

巨细胞病毒(CMV)前葡萄膜炎和血管内皮炎发生于免疫功能正常的个体,可能表现为 Posner-Schlossman 综合征或 Fuchs 葡萄膜炎综合征。该病症可能在眼部手术后首次出现,也可能在使用氟轻松持续类固醇药物输送植入物后或在使用前列腺素类似物治疗青光眼时出现。我们报告了首例非人类免疫缺陷病毒感染个体在使用环孢素 A 0.05%眼用乳液治疗有症状的干眼症后出现 CMV 前葡萄膜炎的病例。

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