Lund G, Morin R L, Olivari M T, Ring W S
Department of Radiology, University of Minnesota Hospitals, Minneapolis.
J Heart Transplant. 1988 Jul-Aug;7(4):274-9.
Myocardial proton T2 relaxation measurements were performed on five normal subjects over 4 weeks (20 measurements) and on nine heart transplant recipients (35 measurements). All magnetic resonance measurements were performed with a 1 T system. All patients had endomyocardial biopsy the same day as magnetic resonance imaging. Results of biopsies were normal on 32 occasions and abnormal three times (two cases of acute rejection and one case of myocardial edema). T2 values for normal subjects were 46.6 +/- 8.1 and 46.9 +/- 4.9 msec (septum and left ventricular free wall, respectively). T2 values for transplant recipients with normal results of biopsies were 44.5 +/- 7.8 and 43.1 +/- 7.5 msec. T2 values in three patients with abnormal results from biopsies were elevated (69 +/- 7.6 msec, range 59.7 to 77.6 msec). The results show similar values in normal subjects and transplant recipients with normal results from biopsies. Increased T2 values in three patients with abnormal results from biopsies indicate that relaxation time measurements may be of value to identify patients at risk of rejection.
对5名正常受试者进行了为期4周的心肌质子T2弛豫测量（共20次测量），并对9名心脏移植受者进行了测量（共35次测量）。所有磁共振测量均使用1T系统进行。所有患者在进行磁共振成像的同一天接受了心内膜心肌活检。活检结果在32次中正常，3次异常（2例急性排斥反应和1例心肌水肿）。正常受试者的T2值分别为46.6±8.1和46.9±4.9毫秒（分别为室间隔和左心室游离壁）。活检结果正常的移植受者的T2值分别为44.5±7.8和43.1±7.5毫秒。3例活检结果异常患者的T2值升高（69±7.6毫秒，范围为59.7至77.6毫秒）。结果显示，正常受试者和活检结果正常的移植受者的T2值相似。3例活检结果异常患者的T2值升高表明，弛豫时间测量可能有助于识别有排斥反应风险的患者。
