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一项关于颈椎硬脊膜撕裂的表现、治疗及结果的多中心研究。

A Multicenter Study of the Presentation, Treatment, and Outcomes of Cervical Dural Tears.

作者信息

O'Neill Kevin R, Fehlings Michael G, Mroz Thomas E, Smith Zachary A, Hsu Wellington K, Kanter Adam S, Steinmetz Michael P, Arnold Paul M, Mummaneni Praveen V, Chou Dean, Nassr Ahmad, Qureshi Sheeraz A, Cho Samuel K, Baird Evan O, Smith Justin S, Shaffrey Christopher, Tannoury Chadi A, Tannoury Tony, Gokaslan Ziya L, Gum Jeffrey L, Hart Robert A, Isaacs Robert E, Sasso Rick C, Bumpass David B, Bydon Mohamad, Corriveau Mark, De Giacomo Anthony F, Derakhshan Adeeb, Jobse Bruce C, Lubelski Daniel, Lee Sungho, Massicotte Eric M, Pace Jonathan R, Smith Gabriel A, Than Khoi D, Riew K Daniel

机构信息

OrthoIndy, Indianapolis, IN, USA.

Toronto Western Hospital, Toronto, Ontario, Canada.

出版信息

Global Spine J. 2017 Apr;7(1 Suppl):58S-63S. doi: 10.1177/2192568216688186. Epub 2017 Apr 1.

Abstract

STUDY DESIGN

Retrospective multicenter case series study.

OBJECTIVE

Because cervical dural tears are rare, most surgeons have limited experience with this complication. A multicenter study was performed to better understand the presentation, treatment, and outcomes following cervical dural tears.

METHODS

Multiple surgeons from 23 institutions retrospectively identified 21 rare complications that occurred between 2005 and 2011, including unintentional cervical dural tears. Demographic data and surgical history were obtained. Clinical outcomes following surgery were assessed, and any reoperations were recorded. Neck Disability Index (NDI), modified Japanese Orthopaedic Association (mJOA), Nurick classification (NuC), and Short-Form 36 (SF36) scores were recorded at baseline and final follow-up at certain centers. All data were collected, collated, and analyzed by a private research organization.

RESULTS

There were 109 cases of cervical dural tears among 18 463 surgeries performed. In 101 cases (93%) there was no clinical sequelae following successful dural tear repair. There were statistical improvements ( < .05) in mJOA and NuC scores, but not NDI or SF36 scores. No specific baseline or operative factors were found to be associated with the occurrence of dural tears. In most cases, no further postoperative treatments of the dural tear were required, while there were 13 patients (12%) that required subsequent treatment of cerebrospinal fluid drainage. Analysis of those requiring further treatments did not identify an optimum treatment strategy for cervical dural tears.

CONCLUSIONS

In this multicenter study, we report our findings on the largest reported series (n = 109) of cervical dural tears. In a vast majority of cases, no subsequent interventions were required and no clinical sequelae were observed.

摘要

研究设计

回顾性多中心病例系列研究。

目的

由于颈椎硬脊膜撕裂很少见,大多数外科医生对这种并发症的经验有限。进行一项多中心研究以更好地了解颈椎硬脊膜撕裂后的表现、治疗及结果。

方法

来自23家机构的多名外科医生回顾性地确定了2005年至2011年间发生的21例罕见并发症,包括意外的颈椎硬脊膜撕裂。获取了人口统计学数据和手术史。评估了手术后的临床结果,并记录了任何再次手术情况。在某些中心,在基线和最终随访时记录了颈部残疾指数(NDI)、改良日本骨科协会(mJOA)评分、努里克分类(NuC)和简短健康调查问卷(SF36)评分。所有数据由一家私人研究机构收集、整理和分析。

结果

在18463例手术中发生了109例颈椎硬脊膜撕裂。101例(93%)在硬脊膜撕裂成功修复后无临床后遗症。mJOA和NuC评分有统计学改善(P<0.05),但NDI或SF36评分没有改善。未发现与硬脊膜撕裂发生相关的特定基线或手术因素。在大多数情况下,硬脊膜撕裂术后无需进一步治疗,而有13例患者(12%)需要后续脑脊液引流治疗。对那些需要进一步治疗的患者的分析未确定颈椎硬脊膜撕裂的最佳治疗策略。

结论

在这项多中心研究中,我们报告了关于已报道的最大系列(n = 109)颈椎硬脊膜撕裂的研究结果。在绝大多数病例中,无需后续干预,也未观察到临床后遗症。

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