Bechtel Allison S, Joyce Michael
University of Florida College of Medicine Jacksonville.
Nemours Specialty Care, Jacksonville, FL.
J Pediatr Hematol Oncol. 2018 Jan;40(1):e32-e33. doi: 10.1097/MPH.0000000000000837.
Hemophagocytic lymphohistiocytosis (HLH) is not always suspected at the time of presentation. It is often mistaken for other diagnoses; complicated by the fact that it is often associated with an inciting event that has significant overlap. Kawasaki disease, along with other disorders, such as Ebstein Barr Virus infection, are conditions that may lead HLH. Our patient had a presentation that was consistent with Kawasaki disease on initial presentation, however subsequently met the diagnostic criteria of HLH. It provided an interesting discussion about diagnoses with clinical criteria and how the overlap can sometimes delay or complicate initial diagnosis.
噬血细胞性淋巴组织细胞增生症(HLH)在初诊时并不总是能被怀疑到。它常常被误诊为其他疾病;其复杂性在于它通常与有显著重叠的诱发事件相关。川崎病以及其他疾病,如EB病毒感染,都是可能导致HLH的病症。我们的患者在初次就诊时表现符合川崎病,但随后符合了HLH的诊断标准。这引发了关于依据临床标准进行诊断以及这种重叠有时如何会延迟或使初始诊断复杂化的有趣讨论。