Paediatric Haematology Oncology Service, Department of Paediatric Medicine, Red Cross War Memorial Children's Hospital, School of Child and Adolescent Health, University of Cape Town, Rondebosch, Cape Town, South Africa.
Pediatr Blood Cancer. 2010 Jul 1;54(7):1023-5. doi: 10.1002/pbc.22422.
Kawasaki disease (KD) is a recognised precipitant of haemophagocytic lymphohistiocytosis (HLH). Although KD has been previously described in the developing world, there are no reported cases of KD preceding HLH. We report a case of a child with a persistent rash and unremitting fever consistent with the diagnosis of KD, who was found to have HLH, after intravenous gamma globulin failed to produce a clinical response. The diagnosis was made using the revised diagnostic criteria for HLH from the Histiocyte Society (1994). She fulfilled six of the eight clinical and laboratory criteria needed to make the diagnosis.
川崎病 (KD) 是噬血细胞性淋巴组织细胞增生症 (HLH) 的公认诱因。尽管 KD 以前在发展中国家已有描述，但尚未有报告称 KD 先于 HLH 发生。我们报告了一例患儿持续出现皮疹和持续性发热，符合 KD 的诊断，静脉注射丙种球蛋白后无临床反应，随后被诊断为 HLH。该诊断采用组织细胞协会 (1994 年) 的 HLH 修订诊断标准做出。她符合做出诊断所需的 8 项临床和实验室标准中的 6 项。
