a Lokmanya Tilak Municipal Medical College and General Hospital , Ophthalmology, Mumbai , India.
b Advanced Eye Hospital & Institute , Ophthalmic Plastic Surgery & Ocular Oncology , Navi Mumbai , India.
Ocul Immunol Inflamm. 2018;26(4):527-532. doi: 10.1080/09273948.2017.1306085. Epub 2017 Apr 28.
To report a rare case of Salmonella typhi associated endogenous endophthalmitis in an immunocompetent male and to review the available literature.
Retrospective chart review.
A 28-year-old immunocompetent male presented with a 3-day-old history of pain, redness and diminished vision in his left eye. Conjunctival chemosis, corneal haze, and hypopyon were noted and yellowish exudates filled the vitreous cavity. A detailed elicitation of history revealed that patient had been treated for enteric fever that presented with diarrhea and fever, two weeks prior to current presentation. Blood and vitreous cultures grew Gram negative bacilli, identified as S. typhi. Despite intensive intravitreal and systemic antibiotic therapy, an evisceration had to be performed.
Endogenous endophthalmitis can be one of the rare sequelae of enteric fever and may present in the acute and relapsing phases and often times have a rapidly fulminant course with poor visual outcomes.
报告一例免疫功能正常的男性伤寒沙门氏菌相关性内源性眼内炎,并复习相关文献。
回顾性病历分析。
一名 28 岁免疫功能正常的男性,左眼疼痛、发红和视力下降 3 天。可见结膜水肿、角膜混浊和前房积脓,玻璃体内充满黄色渗出物。详细询问病史后发现,患者两周前曾因腹泻和发热接受过伤寒治疗。血液和玻璃体液培养均生长出革兰氏阴性杆菌,鉴定为伤寒沙门氏菌。尽管进行了玻璃体腔内和全身抗生素治疗,但仍不得不进行眼球摘除术。
内源性眼内炎可能是伤寒的罕见后遗症之一,可在急性和复发性阶段出现,且常呈迅速暴发性病程,视力预后差。