巴西牛体内抗志贺毒素的抗体。
Antibodies to Shiga toxins in Brazilian cattle.
作者信息
Yamamoto Bruno B, Luz Daniela, Abreu Patrícia A E, Gotti Tatiana B, Vasconcellos Silvio A, Piazza Roxane M F, Horton Denise S P Q
机构信息
Laboratório de Bacteriologia, Instituto Butantan, São Paulo, Brazil.
Laboratório de Zoonoses Bacterianas, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil.
出版信息
Toxicon. 2017 Jul;133:58-62. doi: 10.1016/j.toxicon.2017.04.014. Epub 2017 Apr 25.
Cattle are considered a reservoir of Shiga toxin-producing Escherichia coli (STEC). There is no information about the presence of antibodies against Shiga toxins in Brazilian bovine serum. Using ELISA, all sera tested showed antibodies against the two main STEC virulence factors; Stx1 and Stx2. Neutralizing antibodies against Stx1 and/or Stx2 were detected in all but one serum. In conclusion, our results indicated that these animals had been exposed to STEC producing both toxins.
牛被认为是产志贺毒素大肠杆菌（STEC）的宿主。关于巴西牛血清中抗志贺毒素抗体的存在情况尚无相关信息。使用酶联免疫吸附测定法（ELISA），所有检测的血清均显示出针对两种主要STEC毒力因子（Stx1和Stx2）的抗体。除一份血清外，在所有血清中均检测到了针对Stx1和/或Stx2的中和抗体。总之，我们的结果表明这些动物曾接触过产生这两种毒素的STEC。
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