Blum A L, Siewert R
Leber Magen Darm. 1978 Aug;8(4):184-90.
Five different disorders of motility of the pyloric region may be distinguished if direction and velocity of chyme passing through the pylorus are taken into account: 1. Accelerated emptying of food and overacidification of the bulbus duodeni: 2. Bolus emptying of the stomach and rapid increasing hyperosmolarity in the small intestine: 3. Delayed emptying of the stomach and gastric retention: 4. Duodeno-gastric reflux and inflammatory lesions of the gastric mucosa: 5. Other disorders causing pain. Gastric disroders cannot yet be classified on the basis of abnormal motility patterns. It is well known, that the gastric and duodenal motility are regulated by two separate pacemakers located in the distal corpus area and in the bulbus duodeni. Thus it may be speculated that distrubed motility patterns may be due to abnormal pacemaker function.
如果考虑食糜通过幽门的方向和速度,可区分出五种不同的幽门区运动障碍:1. 食物排空加速和十二指肠球部过度酸化;2. 胃团排空和小肠中高渗性迅速增加;3. 胃排空延迟和胃潴留;4. 十二指肠-胃反流和胃黏膜炎症性病变;5. 其他引起疼痛的障碍。目前尚不能根据异常的运动模式对胃部疾病进行分类。众所周知,胃和十二指肠的运动由位于胃体远端区域和十二指肠球部的两个独立起搏器调节。因此,可以推测运动模式紊乱可能是由于起搏器功能异常所致。