Mittal Abhenil, Sharma Sanchit, Gupta Vineet Govinda, Ragesh R, Nischal Neeraj, Gogia Ajay, Soneja Manish, Das Chandan J, Sharma S K
Department of Internal Medicine.
Department of Medical Oncology, Dr Bheem Rao Ambedkar Institute Rotary Cancer Hospital.
J Assoc Physicians India. 2017 Feb;65(2):78-81.
Cancer of unknown primary accounts for almost 4-5% of all invasive cancers and consists of tumors from various primary sources with considerable heterogeneity in biology and behaviour. Most of these tumors present with symptoms due to distant metastasis. Histology, immunohistochemistry and molecular profiling is the mainstay for diagnosis. In most cases of adenocarinoma associated with paraneoplastic acral vascular syndrome (PAVS), a site in the lung, ovary or uterus is discernible. Here we report a case of metastatic adenoarcinoma of unknown primary presenting as PAVS, a case which to the best of our knowledge has not been reported in published literature.
原发灶不明的癌症占所有浸润性癌症的近4%-5%，由来自各种原发部位的肿瘤组成，在生物学和行为方面具有相当大的异质性。这些肿瘤大多因远处转移而出现症状。组织学、免疫组织化学和分子分析是诊断的主要方法。在大多数与副肿瘤性肢端血管综合征（PAVS）相关的腺癌病例中，肺部、卵巢或子宫的某个部位是可以辨别的。在此，我们报告一例以PAVS表现的原发灶不明的转移性腺癌病例，据我们所知，该病例在已发表的文献中尚未见报道。
