Mugundhan Krishnan, Arasi K V, Balamurugan N, Chandrasekaran P, Thiruvarutchelvan K, Sivakumar S
Senior Assistant Professor of Neurology.
Senior Assistant Professor of Urology.
J Assoc Physicians India. 2017 Feb;65(2):92-93.
Metastatic prostatic carcinoma commonly involves bones and extra pelvic lymph nodes. CNS involvement is unusual and particularly the occurence of leptomeningeal metastasis is extremely rare, with few cases described in the literature.1 The reported incidence at autopsy vary from 0.6 to 4.4 percent.2 We report a 65 year old male who presented with multiple cranial nerve palsies due to leptomeningeal metastasis in carcinoma prostate treated with orchidectomy and planned for radiotherapy and antiandrogen therapy.
转移性前列腺癌通常累及骨骼和盆腔外淋巴结。中枢神经系统受累并不常见，尤其是软脑膜转移的发生极为罕见，文献中报道的病例很少。1尸检报告的发生率为0.6%至4.4%。2我们报告一例65岁男性，因前列腺癌软脑膜转移出现多发性颅神经麻痹，已接受睾丸切除术，计划进行放疗和抗雄激素治疗。
