School of Business and Economics, University of Jyvaskyla, Finland.
School of Business and Economics, University of Jyvaskyla, Finland.
Soc Sci Med. 2017 Sep;188:191-200. doi: 10.1016/j.socscimed.2017.04.030. Epub 2017 Apr 21.
This paper uses longitudinal survey data linked to administrative registers to examine socioeconomic gradients in health, particularly whether the effects of genetic endowments interact with the socioeconomic resources of the parental household. We find that genetic risk scores contribute to adult health measured by biomarkers. This result is consistent with the findings from genome-wide association studies. Socioeconomic gradients in health differ based on biomarker and resource measures. Family education is negatively related to obesity and the waist-hip ratio, and family income is negatively related to low-density lipoprotein cholesterol and triglyceride levels. Parental resources do not modify the effects of genetic endowment on adult health. However, there is evidence for gene-family income interactions for triglyceride levels, particularly among women.
本文利用纵向调查数据与行政登记数据，研究了健康方面的社会经济梯度，特别是遗传禀赋与父母家庭社会经济资源之间的相互作用。我们发现，遗传风险评分会影响生物标志物测量的成年健康。这一结果与全基因组关联研究的结果一致。健康方面的社会经济梯度因生物标志物和资源衡量标准的不同而有所差异。家庭教育与肥胖和腰臀比呈负相关，家庭收入与低密度脂蛋白胆固醇和甘油三酯水平呈负相关。父母资源不会改变遗传禀赋对成年人健康的影响。然而，有证据表明，甘油三酯水平存在基因-家庭收入的相互作用，尤其是在女性中。
