Zweifler Richard M
Ochsner Health System, 1514 Jefferson Highway, New Orleans, LA 70121.
Prog Cardiovasc Dis. 2017 May-Jun;59(6):527-533. doi: 10.1016/j.pcad.2017.04.004. Epub 2017 Apr 27.
Nearly 800,000 strokes occur in the United States each year, and stroke is the leading cause of preventable permanent disability. Timely recognition and treatment are imperative to reduce stroke-related morbidity and mortality. Given the evidence supporting intravenous thrombolysis and mechanical thrombectomy for ischemic stroke, stroke symptoms must be rapidly identified and mimics quickly excluded prior to therapeutic decisions. Intravenous tissue plasminogen activator is recommended for all qualified patients and patients with presentations suggesting large vessel occlusion should be evaluated for mechanical thrombectomy. Time to treatment is the most important prognostic factor for clinical outcome, highlighting the importance of reliable and efficient local and regional systems of care.
在美国，每年有近80万人中风，中风是可预防的永久性残疾的主要原因。及时识别和治疗对于降低与中风相关的发病率和死亡率至关重要。鉴于有证据支持对缺血性中风进行静脉溶栓和机械取栓，在做出治疗决策之前，必须迅速识别中风症状并快速排除类似症状。建议所有符合条件的患者使用静脉注射组织纤溶酶原激活剂，对于提示大血管闭塞的患者应评估是否进行机械取栓。治疗时间是临床结果最重要的预后因素，这凸显了可靠且高效的地方和区域医疗系统的重要性。
