Birkenbihl Rainer P, Liu Shouan, Somssich Imre E
Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, Carl-von-Linné Weg 10, 50829 Koeln, Germany.
College of Plant Sciences, Jilin University, 130062 Changchun, China.
Curr Opin Plant Biol. 2017 Aug;38:1-9. doi: 10.1016/j.pbi.2017.04.004. Epub 2017 Apr 27.
Rapid and massive transcriptional reprogramming upon pathogen recognition is the decisive step in plant-phytopathogen interactions. Plant transcription factors (TFs) are key players in this process but they require a suite of other context-specific co-regulators to establish sensory transcription regulatory networks to bring about host immunity. Molecular, genetic and biochemical studies, particularly in the model plants Arabidopsis and rice, are continuously uncovering new components of the transcriptional machinery that can selectively impact host resistance toward a diverse range of pathogens. Moreover, detailed studies on key immune regulators, such as WRKY TFs and NPR1, are beginning to reveal the underlying mechanisms by which defense hormones influence the function of these factors. Here we provide a short update on such recent developments.
病原体识别后迅速而大规模的转录重编程是植物与植物病原体相互作用的决定性步骤。植物转录因子(TFs)是这一过程中的关键参与者,但它们需要一系列其他特定背景的共调节因子来建立传感转录调控网络,以实现宿主免疫。分子、遗传和生化研究,特别是在模式植物拟南芥和水稻中的研究,不断揭示转录机制的新成分,这些成分可以选择性地影响宿主对多种病原体的抗性。此外,对关键免疫调节因子,如WRKY TFs和NPR1的详细研究,开始揭示防御激素影响这些因子功能的潜在机制。在此,我们简要介绍一下这些最新进展。