Busel Gennadiy A, Watson J Tracy
Department of Orthopaedic Surgery, Saint Louis University School of Medicine, Saint Louis, MO, United States.
J Orthop. 2017 Apr 17;14(2):308-312. doi: 10.1016/j.jor.2017.04.001. eCollection 2017 Jun.
To evaluate mechanically superior method of pilon fracture fixation by comparing axial stiffness between anterolateral and medial tibial locking plates in a cadaveric fracture model.
Eight matched pairs of fresh frozen cadaver specimens (lower limb after through-knee disarticulation) were used to eliminate confounder of bone quality. Simulated pilon fractures were created so that each pair represented either varus or valgus fracture pattern (AO 43-A2) with associated fibular fractures (transverse or comminuted). Specimens were plated with DePuy anterolateral or medial locking plate and axial load applied, measuring displacement at the fracture site. Each lower extremity was tested with a fracture wedge in place and removed to mimic comminution. Average force at which failure occurred was compared between the two fixation methods, for varus and valgus fracture pattern respectively, with the use of a Mann-Whitney test.
On average, medial plate fixation of varus fractures resulted in 2.27 times (range of 1.6-3.9) greater load prior to failure as compared to anterolateral plate. Similarly, valgus simulated fractures tolerated 1.6 times (range 1.12-2.34) higher force prior to failure if anterolateral plate was applied versus medial plate. Analysis utilizing the Mann-Whitney test for fracture patterns vs plate configuration approached statistical significance (p = 0.081 varus failure and p = 0.386 valgus failure).
Lateral plate fixation is biomechanically superior for pilon fractures resulting from valgus force as evident by comminuted fibular fracture. Similarly, medial plate location resulted in improved stiffness in compression for varus type fractures, evident by transverse fibular fracture. We approached statistical significance, however our lack of power regarding adequate sample size is an issue that is consistent with other biomechanical studies in this area.
通过在尸体骨折模型中比较胫骨前外侧锁定钢板和内侧锁定钢板的轴向刚度,评估机械性能更优的pilon骨折固定方法。
使用八对匹配的新鲜冷冻尸体标本(经膝关节离断后的下肢)以消除骨质量的混杂因素。制造模拟pilon骨折,使每对标本代表内翻或外翻骨折模式(AO 43 - A2)以及相关的腓骨骨折(横行或粉碎性)。用DePuy前外侧或内侧锁定钢板固定标本并施加轴向载荷,测量骨折部位的位移。每个下肢在骨折楔形块就位和移除的情况下进行测试,以模拟粉碎情况。分别使用Mann-Whitney检验比较两种固定方法在内外翻骨折模式下发生失效时的平均力。
平均而言,与前外侧钢板相比,内翻骨折的内侧钢板固定在失效前承受的载荷大2.27倍(范围为1.6 - 3.9)。同样,如果应用前外侧钢板而非内侧钢板,外翻模拟骨折在失效前能承受的力高1.6倍(范围为1.12 - 2.34)。利用Mann-Whitney检验对骨折模式与钢板配置进行分析接近统计学显著性(内翻失效p = 0.081,外翻失效p = 0.386)。
外侧钢板固定对于由外翻力导致的伴有粉碎性腓骨骨折的pilon骨折在生物力学上更优。同样,内侧钢板位置对于伴有横行腓骨骨折的内翻型骨折在压缩时刚度有所提高。我们接近了统计学显著性,然而我们样本量不足导致的检验效能问题是与该领域其他生物力学研究一致的一个问题。