预测老年住院重症肌无力患者预后的因素：一项全国性数据库研究。
Factors predicting the outcomes of elderly hospitalized myasthenia gravis patients: a national database study.
作者信息
Tiamkao Somsak, Pranboon Sineenard, Thepsuthammarat Kaewjai, Sawanyawisuth Kittisak
机构信息
Department of Medicine, Faculty of Medicine.
The Neuroscience Research and Development Group.
出版信息
Int J Gen Med. 2017 Apr 20;10:131-135. doi: 10.2147/IJGM.S129075. eCollection 2017.
BACKGROUND
Myasthenia gravis (MG) in elderly populations is increasing. This study aimed to evaluate predictors for treatment outcomes in elderly hospitalized MG patients using the national database.
METHODS
We collected data of elderly hospitalized MG patients from the National Health Security Office from October 2009 to September 2010. Predictors for treatment outcomes were examined.
RESULTS
During the study period, 1,948 identified MG patients were admitted to hospitals throughout Thailand. Of those, 441 patients (22.64%) were aged ≥ 60 years. There were 66 patients (14.97%) who had poor outcomes. There were only three significant factors in the final model. Presence of pneumonia, use of mechanical ventilators, and septicemia had adjusted odds ratios (95% confidence interval) of 2.83 (1.03, 7.75), 5.33 (2.24, 12.72), and 4.47 (1.86, 10.75), respectively.
CONCLUSION
Pneumonia, being on a mechanical ventilator, and septicemia were independent factors associated with poor treatment outcomes in elderly hospitalized MG patients according to national data.
背景
老年人群中的重症肌无力（MG）病例正在增加。本研究旨在利用国家数据库评估老年住院MG患者治疗结果的预测因素。
方法
我们收集了2009年10月至2010年9月期间泰国国家健康保险办公室的老年住院MG患者数据。对治疗结果的预测因素进行了检查。
结果
在研究期间，泰国各地共有1948例确诊的MG患者入院。其中，441例患者（22.64%）年龄≥60岁。有66例患者（14.97%）治疗结果不佳。最终模型中只有三个显著因素。肺炎、使用机械通气和败血症的调整后比值比（95%置信区间）分别为2.83（1.03，7.75）、5.33（2.24，12.72）和4.47（1.86，10.75）。
结论
根据国家数据，肺炎、使用机械通气和败血症是老年住院MG患者治疗结果不佳的独立相关因素。
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