Ciepłoch Aleksandra, Rutkowska Karolina, Oprządek Jolanta, Poławska Ewa
Department of Animal Improvement, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Postępu 36A, Jastrzębiec, 05-552 Magdalenka, Poland.
Genes Genomics. 2017;39(5):461-471. doi: 10.1007/s13258-017-0525-8. Epub 2017 Mar 3.
The main purpose of present review is to describe and organize autosomal recessive disorders (arachnomelia, syndactylism, osteopetrosis, dwarfism, crooked tail syndrome, muscular hyperplasia, glycogen storage disease, protoporphyria), which occur among beef cattle, and methods that can be applied to detect these defects. Prevalence of adverse alleles in beef breeds happens due to human activity-selections of favorable features, e.g. developed muscle tissue. Unfortunately, carriers of autosomal recessive diseases are often characterized by these attributes. Fast and effective identification of individuals, that may carry faulty genes, can prevent economical losses.
本综述的主要目的是描述和梳理肉牛中出现的常染色体隐性疾病(蜘蛛状肢畸形、并指畸形、骨硬化症、侏儒症、弯尾综合征、肌肉增生、糖原贮积病、原卟啉症)以及可用于检测这些缺陷的方法。肉牛品种中不良等位基因的流行是由于人类对有利性状(如发达的肌肉组织)的选择活动导致的。不幸的是,常染色体隐性疾病的携带者往往具有这些特征。快速有效地识别可能携带缺陷基因的个体可以避免经济损失。