Mullen Mary M, Divine Laura M, Hagemann Ian S, Babb Sheri, Powell Matthew A
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, Alvin J. Siteman Cancer Center, St Louis, MO, USA.
Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Gynecol Oncol Rep. 2017 Apr 11;20:121-124. doi: 10.1016/j.gore.2017.04.004. eCollection 2017 May.
• mutations play a significant role in gynecologic malignancy.• may be involved in the sarcomagenesis of endometrial adenosarcoma.•The knowledge of a genetic mutation can help clarify a patient's medical history.
• 突变在妇科恶性肿瘤中起重要作用。
• 可能参与子宫内膜腺肉瘤的肉瘤发生过程。
• 了解基因突变有助于厘清患者的病史。