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眼眶转移性前列腺癌作为疾病的首发表现。

Metastatic prostate carcinoma to the orbit as the first presentation of disease.

作者信息

AufderHeide Adam C, Bernard Benjamin J, Mollman Reid A, Hromas Alan R, Camarata Paul J, Hylton Phillip D, Ebersole Koji C, Sokol Jason A

机构信息

a Department of Ophthalmology , University of Kansas Medical Center , Kansas City , Kansas , USA.

b University of Missouri-Kansas City School of Medicine , Kansas City , Missouri.

出版信息

Orbit. 2017 Aug;36(4):234-236. doi: 10.1080/01676830.2017.1310257. Epub 2017 May 1.

Abstract

Prostate carcinoma is a common tumor of the older adult male. It is associated with bony metastases, particularly to the axial skeleton. We present two case histories; in both cases, the patients had no prior history of prostate carcinoma. Both cases were diagnosed with CT imaging, elevated PSA, and biopsy. Additionally, they were treated with surgical resection and hormone modulation therapy. While bony metastases are frequently associated with advanced disease, they can also be a cause of presenting symptoms. The CT imaging in these two cases showed the classic hyperostotic findings of prostate cancer. Prostate cancer may cause osteoblastic lesions in contrast to other metastatic bone lesions, which cause destructive osteolytic lesions. During excisional surgery, the tumor was inspected and many stalactite-like lesions were present on the gross sample. We present these and compare them to the CT imaging.

摘要

前列腺癌是老年男性常见的肿瘤。它与骨转移有关,尤其是向中轴骨骼转移。我们呈现两个病例;在这两个病例中,患者既往均无前列腺癌病史。两个病例均通过CT成像、PSA升高及活检确诊。此外,他们接受了手术切除和激素调节治疗。虽然骨转移常与晚期疾病相关,但它们也可能是出现症状的原因。这两个病例的CT成像显示了前列腺癌典型的骨质增生表现。与其他导致溶骨性破坏病变的转移性骨病变不同,前列腺癌可能导致成骨性病变。在切除手术中,对肿瘤进行了检查,大体标本上有许多钟乳石样病变。我们展示这些病变并将它们与CT成像进行比较。

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