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降胸段和胸腹主动脉瘤的再次手术修复。

Reoperative repair of descending thoracic and thoracoabdominal aneurysms.

机构信息

Department of Cardiothoracic Surgery, Weill Cornell Medical College, New York, NY, USA.

出版信息

Eur J Cardiothorac Surg. 2017 Sep 1;52(3):501-507. doi: 10.1093/ejcts/ezx072.

Abstract

OBJECTIVES

To evaluate the results of reoperation on descending thoracic and thoracoabdominal aneurysms.

METHODS

Sixty-nine consecutive patients undergoing reoperative aneurysm repair (20 descending thoracic and 49 thoracoabdominal) were compared to 602 contemporary primary repairs. Propensity matching was used to reduce observable differences in preoperative characteristics.

RESULTS

The reoperation group was younger (60.2 vs 65.3 years, P = 0.005) and less were extent I or II (28.6% vs 76%, P < 0.001). In the reoperation group, 82.6% were repaired with clamp-and-sew, 14.5% circulatory arrest and 2.9% partial bypass versus the primary surgery group 62.1%, 8.1% and 29.7%, respectively (P < 0.001). In the reoperation versus primary surgery group, respectively, spinal drainage was used in 73.9% vs 83.7% (P = 0.05), intercostal reimplantation in 11.6% vs 44.2% (P < 0.001), and cold renal perfusion in 36.2% vs 19.8% (P = 0.001). Operative mortality was comparable (8.7% vs 5.3% primary, P = 0.25) but the reoperative extent I subgroup had higher mortality (20% vs 3.1%; P = 0.04). Incidence of major complications was comparable (stroke 0 vs 0.9%, tracheostomy 5.8% vs 8%, renal failure 7.2% vs 5%, spinal cord injury 4.3% vs 2.7%; P > 0.05 for all variables), with the exception of myocardial infarction (2.9% vs 0.5%, P = 0.028). Five-year survival was 57.6% in reoperations and 58% in the primary surgery group (P = 0.878). No differences in the in-hospital and follow-up outcomes were found in the propensity matched comparison.

CONCLUSIONS

Reoperative repair of descending thoracic and thoracoabdominal aneurysms can be safely performed with reasonable in-hospital and follow-up outcomes compared to primary aneurysm repair.

摘要

目的

评估降胸段和胸腹主动脉瘤再次手术的结果。

方法

将 69 例接受再次手术动脉瘤修复(20 例降胸段,49 例胸腹段)的患者与 602 例同期初次手术患者进行比较。采用倾向评分匹配法减少术前特征的可观察差异。

结果

再次手术组年龄较小(60.2 岁 vs 65.3 岁,P=0.005),I 型或 II 型比例较低(28.6% vs 76%,P<0.001)。再次手术组中,82.6%采用夹闭缝合,14.5%采用体外循环停循环,2.9%采用部分旁路,而初次手术组分别为 62.1%、8.1%和 29.7%(P<0.001)。再次手术组与初次手术组相比,分别有 73.9%和 83.7%使用脊髓引流(P=0.05)、11.6%和 44.2%肋间神经再植入(P<0.001)、36.2%和 19.8%采用肾低温灌注(P=0.001)。手术死亡率相似(8.7% vs 5.3%,初次手术,P=0.25),但 I 型再次手术亚组死亡率较高(20% vs 3.1%;P=0.04)。主要并发症发生率相似(中风 0 例 vs 0.9%,气管切开术 5.8% vs 8%,肾衰竭 7.2% vs 5%,脊髓损伤 4.3% vs 2.7%;所有变量 P>0.05),但心肌梗死除外(2.9% vs 0.5%,P=0.028)。再次手术组和初次手术组的 5 年生存率分别为 57.6%和 58%(P=0.878)。在倾向评分匹配比较中,未发现住院和随访结果的差异。

结论

与初次动脉瘤修复相比,降胸段和胸腹主动脉瘤再次手术治疗可安全进行,且住院和随访结果合理。

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