Sakata Tomoki, Nakaya Mitsuru, Otsu Masayoshi, Sunazawa Toru, Wakabayashi Yutaka
Tex Heart Inst J. 2017 Apr 1;44(2):144-146. doi: 10.14503/THIJ-16-5822. eCollection 2017 Apr.
A 50-year-old man with no history of cardiovascular disease was referred to our hospital because of an abnormal electrocardiogram. Echocardiograms and computed tomograms revealed a 9-mm mass on the underside of an aortic valve leaflet. We chose surgical treatment, to prevent embolic events. The tumor's appearance and intraoperative frozen section were consistent with myxoma. We resected the tumor and its attachment, including the free margin of the aortic valve leaflet, and repaired the defect with use of a glutaraldehyde-treated autologous pericardial patch. The postoperative histopathologic diagnosis was papillary fibroelastoma. Six months later, echocardiograms showed mild aortic regurgitation and no recurrence of the aortic valve mass. Papillary fibroelastoma and myxoma can be difficult to distinguish intraoperatively, yet the diagnosis has considerable influence on the surgical strategy, including whether valve-sparing excision is an option. Therefore, it is necessary to at least suspect both entities if the tumor characteristics are unusual. This case is instructive for surgeons and pathologists.
一名无心血管疾病史的50岁男性因心电图异常被转诊至我院。超声心动图和计算机断层扫描显示主动脉瓣叶下侧有一个9毫米的肿块。为预防栓塞事件,我们选择了手术治疗。肿瘤的外观和术中冰冻切片与黏液瘤一致。我们切除了肿瘤及其附着部位,包括主动脉瓣叶的游离缘,并使用戊二醛处理的自体心包补片修复缺损。术后组织病理学诊断为乳头状纤维弹性瘤。六个月后,超声心动图显示轻度主动脉瓣反流,主动脉瓣肿块无复发。乳头状纤维弹性瘤和黏液瘤在术中可能难以区分,但诊断对手术策略有相当大的影响,包括是否选择保留瓣膜的切除术。因此,如果肿瘤特征不寻常,至少有必要怀疑这两种病变。该病例对外科医生和病理学家具有指导意义。