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大头金属对金属髋关节置换术的后遗症:现状与未来展望。

Sequelae of large-head metal-on-metal hip arthroplasties: Current status and future prospects.

作者信息

van Lingen Christiaan P, Zagra Luigi M, Ettema Harmen B, Verheyen Cees C

机构信息

Isala Clinics, Department of Orthopaedic Surgery and Traumatology, Zwolle, The Netherlands.

IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

出版信息

EFORT Open Rev. 2017 Mar 13;1(10):345-353. doi: 10.1302/2058-5241.1.160014. eCollection 2016 Oct.

Abstract

Large-head metal-on-metal (MoM) bearings were re-popularised in the late 1990s with the introduction of modern hip resurfacing (HR), followed closely by large metal head total hip arthroplasty (THA). A worldwide increase in the use of MoM hip arthroplasty subsequently saw a sharp decline, due to serious complications.MoM was rapidly adopted in the early 2000s until medical device alerts were issued by government regulatory agencies and national and international organisations, leading to post-marketing surveillance and discontinuation of these implants.Guidelines for MoM hip implant follow-up differ considerably between regulatory authorities worldwide; this can in part be attributed to missing or conflicting evidence.The authors consider that the use of large-head MoM THA should be discontinued. MoM HR should be approached with caution and, when considered, should be used only in patients who meet all of the recommended selection criteria, which limits its indications considerably.The phased introduction of new prostheses should be mandatory in future. Close monitoring of outcomes and long-term follow-up is also necessary for the introduction of new prostheses. Cite this article: van Lingen CP, Zagra LM, Ettema HB, Verheyen CC. Sequelae of large-head metal-on-metal hip arthroplasties: current status and future prospects. EFORT Open Rev 2016;1:345-353. DOI: 10.1302/2058-5241.1.160014.

摘要

大尺寸金属对金属(MoM)轴承在20世纪90年代末随着现代髋关节表面置换术(HR)的引入而重新流行起来,紧随其后的是大尺寸金属头全髋关节置换术(THA)。由于严重并发症,随后全球范围内MoM髋关节置换术的使用量急剧下降。MoM在21世纪初迅速被采用,直到政府监管机构以及国家和国际组织发布医疗器械警报,导致这些植入物进行上市后监测并停产。全球监管机构对MoM髋关节植入物随访的指导方针差异很大;这部分可归因于证据缺失或相互矛盾。作者认为应停止使用大尺寸MoM THA。对于MoM HR应谨慎对待,并且在考虑使用时,应仅用于符合所有推荐选择标准的患者,这极大地限制了其适应症。未来应强制分阶段引入新假体。对于新假体的引入,密切监测结果和长期随访也是必要的。引用本文:van Lingen CP, Zagra LM, Ettema HB, Verheyen CC。大尺寸金属对金属髋关节置换术的后遗症:现状与未来前景。EFORT Open Rev 2016;1:345 - 353。DOI: 10.1302/2058 - 5241.1.160014。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b1e/5367524/1cbfdb247139/eor-1-345-g001.jpg

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