Department of Chemistry, Xinzhou Teachers University, Xinzhou, 034000, Shanxi, China.
Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Jiawei Li and Caixia Yin, Shanxi University, Taiyuan, China.
Curr Med Chem. 2019;26(21):3958-4002. doi: 10.2174/0929867324666170428110724.
In recent years, fluorescent probes have recently attracted attention from researchers. As a vital trace metal element, Cu2+ has an important role in the human body and environment. Therefore, the development and design of Cu2+ small-molecular fluorescent probes has been an active research area. This review focuses on the developments in the area of small-molecular fluorescent probes for Cu2+ in biological applications according to different sensing mechanisms including charge transfer (CT), electron transfer, energy transfer, excited-state intramolecular proton transfer (ESIPT).
近年来，荧光探针受到了研究人员的关注。作为一种重要的痕量金属元素，Cu2+ 在人体和环境中都具有重要的作用。因此，Cu2+小分子荧光探针的开发和设计一直是一个活跃的研究领域。本综述根据不同的传感机制，包括电荷转移（CT）、电子转移、能量转移和激发态分子内质子转移（ESIPT），重点介绍了生物应用中小分子荧光探针检测 Cu2+的发展。
