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使用基于光纤的超连续谱装置测量大脑和视网膜组织在近红外范围内的光谱衰减。

Spectral attenuation of brain and retina tissues in the near-infrared range measured using a fiber-based supercontinuum device.

作者信息

Saldaña-Díaz José Eduardo, Jarabo Sebastián, Salgado-Remacha Francisco Javier, Perdices Lorena, Pinilla Isabel, Sánchez-Cano Ana

机构信息

Universidad de Zaragoza, Departamento de Física Aplicada, Pedro Cerbuna 12, E-50009, Zaragoza, Spain.

Universidad Nacional de Huancavelica, Departamento Académico de Ciencias Básicas, Facultad de Ciencias e Ingeniería, Huancavelica, Peru.

出版信息

J Biophotonics. 2017 Sep;10(9):1105-1109. doi: 10.1002/jbio.201600292. Epub 2017 May 2.

Abstract

A novel setup for the efficient constant optical measurements of biological tissues in the near infrared is presented. The system combines the use of a fiber-based supercontinuum source with a simple optics fiber collimator. This configuration allows a wide spectral range of measurement and, at the same time, can efficiently filter the straightforward transmitted light while avoiding scattered light. As a performance example, the optical characterization of rat brain and retina tissues are shown. The attenuation coefficient for both tissues in the near infrared region is also obtained. This technique could be applied in clinical research as a noninvasive method with several potential practical applications.

摘要

本文介绍了一种用于近红外生物组织高效恒定光学测量的新型装置。该系统将基于光纤的超连续谱源与简单的光纤准直器结合使用。这种配置允许进行宽光谱范围的测量,同时可以有效地过滤直接透射光,同时避免散射光。作为性能示例,展示了大鼠脑和视网膜组织的光学特性。还获得了两种组织在近红外区域的衰减系数。该技术可作为一种具有多种潜在实际应用的非侵入性方法应用于临床研究。

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