年龄可能导致轴索性吉兰-巴雷综合征发病率增加。
Age may contribute to the increased frequency of axonal Guillain-Barré syndrome.
作者信息
Hawkes Maximiliano A, Wilken Miguel, Vázquez Gabriel, Farez Mauricio F
机构信息
Department of Neurology, Division of Critical Care Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Department of Neurology, Raúl Carrea Institute for Neurological Research (FLENI), Buenos Aires, Argentina.
出版信息
Muscle Nerve. 2017 Dec;56(6):1171-1173. doi: 10.1002/mus.25679. Epub 2017 May 15.
INTRODUCTION
The frequency of axonal Guillain-Barré syndrome (GBS) varies among countries. Previous studies supporting the high frequency of axonal GBS in South America have been carried out with pediatric populations. We seek to determine the frequency of axonal GBS in both children and adults in South America.
METHODS
This is a retrospective cohort analysis of patients who were diagnosed with GBS between January 2006 and December 2013 in a neurological center in Buenos Aires, Argentina. Adults and children with a diagnosis of GBS were included and classified by applying Ho and colleagues' criteria for axonal GBS.
RESULTS
The study included 105 patients with GBS. Among 58 adults, only 5 individuals were classified as axonal GBS compared with 16 of 47 children. The frequency of axonal GBS was significantly higher in children than in adults (34% vs. 8.6%, P = 0.0001).
DISCUSSION
As shown in a cohort of South American patients, age may impact the frequency of axonal GBS. Muscle Nerve 56: 1311-1313, 2017.
引言
轴索性吉兰-巴雷综合征（GBS）在各国的发病率有所不同。此前支持南美洲轴索性GBS高发的研究是针对儿科人群开展的。我们旨在确定南美洲儿童和成人中轴索性GBS的发病率。
方法
这是一项对2006年1月至2013年12月期间在阿根廷布宜诺斯艾利斯一家神经科中心被诊断为GBS的患者进行的回顾性队列分析。纳入诊断为GBS的成人和儿童，并根据Ho及其同事提出的轴索性GBS标准进行分类。
结果
该研究纳入了105例GBS患者。在58例成人中，只有5例被归类为轴索性GBS，而47例儿童中有16例。儿童中轴索性GBS的发病率显著高于成人（34%对8.6%，P = 0.0001）。
讨论
正如一组南美洲患者所示，年龄可能会影响轴索性GBS的发病率。《肌肉与神经》56: 1311 - 1313, 2017年。
Zotero 插件