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妊娠期糖尿病筛查与诊断的批判性评估及潜在的新概念方法

A critical appraisal and potentially new conceptual approach to screening and diagnosis of gestational diabetes.

作者信息

Petrović Oleg, Belci Dragan

机构信息

a Department of Gynaecology and Obstetrics, Perinatal Unit , University Hospital Centre Rijeka , Rijeka , Croatia.

b Department of Gynaecology , General Hospital Pula , Pula , Croatia.

出版信息

J Obstet Gynaecol. 2017 Aug;37(6):691-699. doi: 10.1080/01443615.2017.1306692. Epub 2017 May 3.

Abstract

The aim of this article was a critical appraisal of current GDM screening and diagnosis status as well as a presentation of a potentially new approach to this perinatologic and public health problem of increasing clinical significance. Medline, EMBASE and Cochrane databases were searched. Most professional organisations recommend universal screening at 24-28 weeks of gestation, while some of them state that selective screening could also be recommended. Expert opinions regarding GDM diagnosis significantly differ throughout the world. Authors call for an open and broad professional and scientific discussion and suggest a combination of screening and diagnosis procedures in a form of one-step 1-h screening method, creation of regional GDM diagnostic criteria and standardisation of outcome-based randomised control trials. They also advise introduction of a conceptually new approach, where the risk of hyperglycaemia rather than insisting on GDM diagnosis itself should be detected.

摘要

本文旨在对当前妊娠期糖尿病(GDM)的筛查与诊断现状进行批判性评估,并针对这一在围产医学和公共卫生领域临床意义日益增加的问题,介绍一种可能的新方法。检索了Medline、EMBASE和Cochrane数据库。大多数专业组织建议在妊娠24 - 28周进行普遍筛查,而其中一些组织表示也可推荐选择性筛查。世界各地关于GDM诊断的专家意见存在显著差异。作者呼吁开展开放且广泛的专业和科学讨论,并建议采用一步法1小时筛查方法的形式组合筛查和诊断程序,制定区域GDM诊断标准以及基于结果的随机对照试验的标准化。他们还建议引入一种概念上的新方法,即检测高血糖风险而非坚持GDM诊断本身。

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