人胎膜、胎盘和蜕膜中白三烯的释放与分娩的关系。

Leukotriene release by human fetal membranes, placenta and decidua in relation to parturition.

作者信息

Rees M C, Di Marzo V, Lopez Bernal A, Tippins J R, Morris H R, Trunbull A C

机构信息

Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford.

出版信息

J Endocrinol. 1988 Sep;118(3):497-500. doi: 10.1677/joe.0.1180497.

DOI:10.1677/joe.0.1180497

PMID:2846741

Abstract

Complete placentas and membranes were obtained from women after uncomplicated singleton pregnancies. Six were collected after labour at term, six after preterm labour and six after elective Caesarean section at term. Leukotriene C4 (LTC4), leukotriene D4 (LTD4) and leukotriene E4 (LTE4) release was examined using a short-term incubation technique. Release by amnion was significantly higher than that by the other tissues for the three modes of delivery. Comparison of LTC4, LTD4 and LTE4 release by individual tissues with regard to the type of delivery showed no significant difference.

摘要

完整的胎盘和胎膜取自单胎妊娠无并发症的女性。其中6例在足月分娩后采集，6例在早产分娩后采集，6例在足月选择性剖宫产术后采集。采用短期孵育技术检测白三烯C4（LTC4）、白三烯D4（LTD4）和白三烯E4（LTE4）的释放情况。在三种分娩方式中，羊膜释放的这些物质显著高于其他组织。就分娩类型而言，各组织释放LTC4、LTD4和LTE4的比较无显著差异。