Berry A D, Reintjes S L, Kepes J J
Department of Pathology and Oncology, University of Kansas, College of Health Sciences, Kansas City.
J Neurosurg. 1988 Nov;69(5):780-4. doi: 10.3171/jns.1988.69.5.0780.
A case of a malignant fibrous histiocytoma (MFH) in the right temporal lobe of a 75-year-old man is reported. The tumor involved the brain and the overlying dura as one continuous mass and had undergone extensive liquefaction necrosis of its center that had a gross appearance similar to that of an abscess. The preoperative computerized tomography scan with injection of contrast material showed the lesion to have central and peripheral enhancement suggestive of metastatic tumor, glioblastoma multiforme, or abscess. Microscopically, the tumor showed the typical features of a MFH with marked acute inflammation in the areas of necrosis. No extracranial sources for this tumor were found clinically. This is the 15th reported case of MFH involving the central nervous system as a primary neoplasm and the first case with gross pathological and radiological features resembling in many respects those of an abscess.
报告了一例75岁男性右颞叶恶性纤维组织细胞瘤（MFH）病例。肿瘤累及脑及覆盖的硬脑膜，形成一个连续的肿块，其中心已发生广泛的液化坏死，大体外观类似脓肿。术前增强计算机断层扫描显示病变有中央和周边强化，提示转移性肿瘤、多形性胶质母细胞瘤或脓肿。显微镜下，肿瘤表现为MFH的典型特征，坏死区域有明显的急性炎症。临床上未发现该肿瘤的颅外来源。这是第15例报告的以原发性肿瘤形式累及中枢神经系统的MFH病例，也是第一例大体病理和放射学特征在许多方面类似于脓肿的病例。
