Sangare A, Cowpli-Boni M, Sanogo I, Cabannes R, Boivin E P
Service d'Hématologie, C.H.U. de Cocody, Abidjan, Côte d'Ivoire.
Med Trop (Mars). 1988 Jul-Sep;48(3):253-7.
The authors report 6 cases of hereditary elliptocytosis during a screening in one thousand (1,000) black persons. The analysis of these cases of elliptocytosis allow to draw the following conclusions: the frequency of the hereditary elliptocytosis varies between 0.6 to 1 per cent in Ivory Coast, the functional and structural analysis of spectrin show a high global frequency of the elliptocytosis of Model I in relation with an abnormally of alpha I domain of spectrin, all the cases detected don't give any clinical trouble.
作者报告了在对1000名黑人进行的一项筛查中发现的6例遗传性椭圆形红细胞增多症。对这些椭圆形红细胞增多症病例的分析得出以下结论：在象牙海岸，遗传性椭圆形红细胞增多症的发病率在0.6%至1%之间；血影蛋白的功能和结构分析显示，与血影蛋白αI结构域异常相关的I型椭圆形红细胞增多症总体发病率较高；所有检测出的病例均未出现任何临床问题。
