食管鳞状乳头状瘤缺乏明确的临床病理联系。
Esophageal squamous papilloma lacks clear clinicopathological associations.
作者信息
Jideh Bilel, Weltman Martin, Wu Yang, Chan Calvin H Y
机构信息
Bilel Jideh, Martin Weltman, Yang Wu, Calvin H Y Chan, Department of Gastroenterology and Hepatology, Nepean Hospital, Sydney, NSW 2747, Australia.
出版信息
World J Clin Cases. 2017 Apr 16;5(4):134-139. doi: 10.12998/wjcc.v5.i4.134.
AIM
To determine the prevalence of esophageal squamous papillomas (ESPs) in a tertiary teaching hospital and to assess for any clinical associations, including relations with esophageal squamous cell carcinomas (SCCs).
METHODS
Data from a total of 6962 upper gastrointestinal endoscopies over a five year period were retrospectively obtained and analysed.
RESULTS
ESP was found in sixteen patients (0.23%). Eight (50%) patients had a high body mass index, seven (44%) had history of cigarette smoking. Reflux esophagitis was found in four (25%) patients. All ESPs were solitary with a mean endoscopic size of 3.8 mm and located in the mid to lower esophagus. Human papilloma virus (HPV) was tested in three (19%) patients and was negative. Esophageal SCC was found in seven patients (0.10%) during the same period. None of the specimens were tested for HPV, and none had associated papillomatous changes.
CONCLUSION
ESP is an uncommon tumour with unclear clinical associations and malignant potential.
目的
确定一家三级教学医院中食管鳞状乳头状瘤（ESPs）的患病率，并评估其任何临床关联，包括与食管鳞状细胞癌（SCCs）的关系。
方法
回顾性获取并分析了五年期间总共6962例上消化道内镜检查的数据。
结果
16例患者（0.23%）发现有食管鳞状乳头状瘤。8例（50%）患者体重指数较高，7例（44%）有吸烟史。4例（25%）患者发现有反流性食管炎。所有食管鳞状乳头状瘤均为单发，内镜下平均大小为3.8毫米，位于食管中下段。3例（19%）患者检测了人乳头瘤病毒（HPV），结果为阴性。同期发现7例患者（0.10%）患有食管鳞状细胞癌。所有标本均未检测HPV，且均无相关的乳头状瘤样改变。
结论
食管鳞状乳头状瘤是一种罕见的肿瘤，其临床关联和恶性潜能尚不清楚。
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