Meyer J E, Sonnenfeld M R, Greenes R A, Stomper P C
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
Radiology. 1988 Dec;169(3):627-8. doi: 10.1148/radiology.169.3.2847232.
The authors performed 601 preoperative needle localization procedures for occult breast abnormalities in 1987. Whereas most previous series have been based on mammograms obtained and interpreted at the reporting institutions, this study population includes a large number of patients (79%) examined and referred from other facilities. One hundred nine cancers were diagnosed in the 601 cases (18%). Biopsies performed for masses yielded a 23% (64 of 278) frequency of cancer and those for calcification, 14% (45 of 323). The benign to malignant ratio (4.5:1) in this mixed group of patients is higher than that cited in reports of other large series. An analysis of the factors that might influence these statistics is presented.
作者在1987年对隐匿性乳腺异常进行了601例术前针定位操作。以往大多数系列研究都是基于在报告机构获取并解读的乳房X光片，而本研究人群包括大量（79%）从其他机构转诊而来并接受检查的患者。601例病例中诊断出109例癌症（18%）。对肿块进行的活检中癌症发生率为23%（278例中的64例），对钙化灶进行的活检中癌症发生率为14%（323例中的45例）。在这个混合患者组中，良性与恶性比例（4.5:1）高于其他大型系列报告中所引用的比例。本文对可能影响这些统计数据的因素进行了分析。
