Principal Author, George Washington University Hospital, Washington, District of Columbia.
Panel Vice-chair, Northwestern University, Chicago, Illinois.
J Am Coll Radiol. 2017 May;14(5S):S272-S281. doi: 10.1016/j.jacr.2017.02.034.
Renal transplantation is the treatment of choice in patients with end-stage renal disease because the 5-year survival rates range from 72% to 99%. Although graft survival has improved secondary to the introduction of newer immunosuppression drugs and the advancements in surgical technique, various complications still occur. Ultrasound is the first-line imaging modality for the evaluation of renal transplants in the immediate postoperative period and for long-term follow-up. In addition to depicting many of the potential complications of renal transplantation, ultrasound can also guide therapeutic interventions. Nuclear medicine studies, CT, and MRI are often helpful as complementary examinations for specific indications. Angiography remains the reference standard for vascular complications and is utilized to guide nonsurgical intervention. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer-reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
肾移植是治疗终末期肾病患者的首选方法,因为其 5 年生存率范围为 72%至 99%。尽管由于新型免疫抑制药物的引入和手术技术的进步,移植物存活率有所提高,但仍会发生各种并发症。超声是评估肾移植术后即刻和长期随访的一线影像学检查方法。除了描绘肾移植的许多潜在并发症外,超声还可以指导治疗干预。核医学研究、CT 和 MRI 通常作为特定适应症的补充检查很有帮助。血管造影仍然是血管并发症的参考标准,并用于指导非手术干预。美国放射学院适宜性标准是针对特定临床情况的循证指南,每年由多学科专家小组进行审查。指南的制定和修订包括对同行评议期刊上的现有医学文献进行广泛分析,并应用成熟的方法学(RAND/UCLA 适宜性方法和推荐评估、制定和评估分级或 GRADE)来评估特定临床情况下的影像学和治疗程序的适宜性。在证据不足或存在争议的情况下,专家意见可以补充现有证据,推荐进行影像学检查或治疗。