Principal Author, NYU Clinical Cancer Center, New York, New York.
Bay Area Breast Surgeons, Emeryville, California; American College of Surgeons.
J Am Coll Radiol. 2017 May;14(5S):S282-S292. doi: 10.1016/j.jacr.2017.02.009.
Women and health care professionals generally prefer intensive follow-up after a diagnosis of breast cancer. However, there are no survival differences between women who obtain intensive surveillance with imaging and laboratory studies compared with women who only undergo testing because of the development of symptoms or findings on clinical examinations. American Society of Clinical Oncology and National Comprehensive Cancer Network guidelines state that annual mammography is the only imaging examination that should be performed to detect a localized breast recurrence in asymptomatic patients; more imaging may be needed if the patient has locoregional symptoms (eg, palpable abnormality). Women with other risk factors that increase their lifetime risk for breast cancer may warrant evaluation with breast MRI. Furthermore, the quality of life is similar for women who undergo intensive surveillance compared with those who do not. There is little justification for imaging to detect or rule out metastasis in asymptomatic women with newly diagnosed stage I breast cancer. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
女性和医疗保健专业人员通常更倾向于在乳腺癌诊断后进行强化随访。然而,与因出现症状或临床检查结果而进行检测的女性相比,接受影像学和实验室研究强化监测的女性在生存方面没有差异。美国临床肿瘤学会和国家综合癌症网络指南指出,每年进行乳房 X 光检查是检测无症状患者局部乳腺癌复发的唯一影像学检查;如果患者出现局部区域症状(例如可触及的异常),可能需要更多的影像学检查。有其他增加乳腺癌终生风险的危险因素的女性可能需要进行乳房 MRI 评估。此外,与未进行强化监测的女性相比,进行强化监测的女性生活质量相似。对于新诊断为 I 期乳腺癌且无症状的女性,影像学检查在检测或排除转移方面的作用有限。美国放射学院适宜性标准是针对特定临床情况的循证指南,每年由多学科专家小组进行审查。指南的制定和修订包括对同行评议期刊的现有医学文献进行广泛分析,并应用成熟的方法学(RAND/UCLA 适宜性方法和推荐评估、制定和评估分级或 GRADE)对特定临床情况下的影像学和治疗程序的适宜性进行评估。在证据不足或存在争议的情况下,专家意见可以补充现有证据,推荐进行影像学检查或治疗。