Park Sihyung, Kim Yang Wook, Lee Yoo Jin, Park Kang Min, Park Jin Han, Kim Bo Mi, Park Bong Soo
Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.
Department of Neurology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.
Am J Case Rep. 2017 May 5;18:498-501. doi: 10.12659/ajcr.902031.
BACKGROUND Polyomavirus nephropathy has emerged as an important cause of graft loss in kidney transplant recipients. Polyomavirus rarely affects the native kidneys of an immunocompetent individual. Until now, polyomavirus nephropathy in native kidneys of an immunocompetent individual has not been reported, as far as we know. CASE REPORT A 34-year-old man was transferred from a local clinic to be evaluated for the cause of azotemia. Serum creatinine was 2.85 mg/dL. We performed renal biopsy to identify the cause of azotemia. The result of kidney biopsy was consisted to polyomavirus nephropathy. CONCLUSIONS We report the first case of polyomavirus nephropathy in native kidneys of an immunocompetent individual.
背景 多瘤病毒肾病已成为肾移植受者移植肾丢失的一个重要原因。多瘤病毒很少影响免疫功能正常个体的自身肾脏。据我们所知，迄今为止，尚未有关于免疫功能正常个体自身肾脏发生多瘤病毒肾病的报道。病例报告 一名34岁男性从当地诊所转诊来评估氮质血症的病因。血清肌酐为2.85mg/dL。我们进行了肾活检以确定氮质血症的病因。肾活检结果符合多瘤病毒肾病。结论 我们报告了首例免疫功能正常个体自身肾脏发生多瘤病毒肾病的病例。
