Gottrand Frédéric, Ley Delphine, Michaud Laurent, Sfeir Rony
Reference Center for Congenital and Malformative Esophageal Disorders, CHU Lille, Univ. Lille2, Lille, France.
Front Pediatr. 2017 Apr 20;5:81. doi: 10.3389/fped.2017.00081. eCollection 2017.
Esophageal atresia (EA) is a rare congenital defect. Data on EA prevalence, management, and long-term outcome are lacking because the available data come from small retrospective series from tertiary referral centers. An international multicenter registry would provide strong epidemiological data from large population-based cohorts on EA prevalence and incidence, treatment, long-term morbidity, and prognosis and would thus provide accurate data for evaluation of the current guidelines for EA management. The future challenge of the new international network on EA, which was created in 2013, is to promote the creation of a collaborative database and further studies.
食管闭锁(EA)是一种罕见的先天性缺陷。由于现有数据来自三级转诊中心的小型回顾性系列研究,因此缺乏关于EA患病率、治疗及长期预后的数据。一个国际多中心登记处将提供来自大型人群队列的强有力的流行病学数据,涵盖EA的患病率、发病率、治疗、长期发病率及预后,从而为评估当前EA管理指南提供准确数据。2013年创建的新的EA国际网络未来面临的挑战是推动建立一个协作数据库并开展进一步研究。