Wolff H, Bieselt R, Matthias M
Klinik für Chirurgie, Humboldt-Universitt zu Berlin.
Zentralbl Chir. 1988;113(17):1081-6.
There are controversial views and discussions on surgical treatment of small cell lung cancer. A retrospective study covering the period from 1959 through 1983 has been conducted by the authors to analyse resective approaches to lung cancer. A total of 2,039 resections for lung cancer included operations on 354 small cell carcinomas according to the WHO nomenclature. Operations were performed on 265 cases of small cell lung cancer by the end of 1977. These were subdivided by stages, with survival rates being determined. An overall five-year survival rate was recorded from 22.8 per cent of the cases with 43.0 per cent in Stage Ia und 21.4 per cent in Stage Ib. Hence, resection of small cell lung cancer is fully supported by the authors for Stage Ia and is conditionally supported for Stage Ib, whereas complex radiotherapy and chemotherapy should be applied to small cell lung cancer in the advanced Stage II and III.
关于小细胞肺癌的外科治疗存在争议性的观点和讨论。作者进行了一项涵盖1959年至1983年期间的回顾性研究,以分析肺癌的切除方法。根据世界卫生组织的命名法,总共2039例肺癌切除术包括对354例小细胞癌的手术。到1977年底,对265例小细胞肺癌进行了手术。这些病例按阶段细分,并确定了生存率。总体五年生存率为22.8%,其中Ia期为43.0%,Ib期为21.4%。因此,作者完全支持对Ia期小细胞肺癌进行切除,对Ib期有条件支持,而对于II期和III期晚期小细胞肺癌应采用综合放疗和化疗。