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阿片类药物依赖与驾驶能力:在维多利亚州拟议的立法变革背景下的综述

Opioid dependence and driving ability: a review in the context of proposed legislative change in Victoria.

作者信息

Lenné Michael G, Dietze Paul, Rumbold Greg, Redman Jennifer R, Triggs Thomas J

机构信息

Accident Research Centre, Monash University, Clayton, VIC, AustraliaTurning Point Alcohol and Drug Centre Inc, Fitzroy, VIC, AustraliaDepartment of Psychology, Monash University, Clayton, VIC, Australia.

出版信息

Drug Alcohol Rev. 2000 Dec;19(4):427-439. doi: 10.1080/713659417.

Abstract

There is debate in Victoria, Australia concerning the effects of various drugs, including opioids, on driving skills and accident rates, and the development of appropriate legislative responses. There are legislative difficulties around drugs and driving because of the lack of adequate epidemiological and performance-based studies. In relation to opioids, although there are studies that have shown the prevalence of opioids in both non-fatal and fatal crashes, these studies do not demonstrate that the use of opioids is associated with any elevated crash risk and they fail to take into account issues regarding tolerance. A review of the performance studies, including only a small number of driving studies, suggests that opioids, and in particular methadone, have limited effects on driving skills. None the less, recommendations have been made in other countries, such as Germany, that place driving restrictions upon methadone clients. This paper reviews the available evidence concerning the effects of opioids on driving skills and accident risk, with reference to the proposed changes to legislation in the area of drugs and driving in Victoria.

摘要

在澳大利亚维多利亚州,人们正在讨论包括阿片类药物在内的各种药物对驾驶技能和事故率的影响,以及制定适当的立法应对措施。由于缺乏足够的流行病学研究和基于驾驶表现的研究,围绕药物与驾驶存在立法难题。关于阿片类药物,尽管有研究表明在非致命和致命撞车事故中都存在阿片类药物,但这些研究并未证明使用阿片类药物会增加任何撞车风险,而且它们没有考虑耐受性问题。对驾驶表现研究(其中仅包括少数驾驶研究)的综述表明,阿片类药物,尤其是美沙酮,对驾驶技能的影响有限。尽管如此,其他国家,如德国,已提出建议,对服用美沙酮的人员实施驾驶限制。本文参考维多利亚州在药物与驾驶领域拟议的立法变更,综述了关于阿片类药物对驾驶技能和事故风险影响的现有证据。

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