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表现为双侧手臂红斑性斑块的原发性皮肤结外自然杀伤细胞/ T细胞淋巴瘤

Primary cutaneous extranodal natural killer/T-cell lymphoma presenting as bilateral erythematous patches on the arms.

作者信息

Moon Ik Jun, Kang Hyun Ji, Lee Mi Woo, Lee Woo Jin

机构信息

Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

出版信息

Indian J Dermatol Venereol Leprol. 2017 Jul-Aug;83(4):453-456. doi: 10.4103/ijdvl.IJDVL_264_16.

Abstract

Natural killer/T-cell lymphoma is a rare, Epstein-Barr virus-associated type of cytotoxic lymphoma thatpresents mainly in the nasal cavity and its vicinity. Very few cases of primary cutaneous extranodal natural killer/T-cell lymphoma have been reported till date. All the previously reported cases of primary cutaneous extranodalnatural killer/T-cell lymphoma presented as lesions resembling cellulitis, subcutaneous nodules or ulcers. We report a rare case which presented as erythematous and purpuric round patches on the arms and was finally diagnosed as primary cutaneous extranodalnatural killer/T-cell lymphoma, following a skin biopsy. The atypical patchy lesions presented a diagnostic challenge. We herein describe this clinically novel atypical patch-like presentation of primary cutaneous extranodalnatural killer/T-cell lymphoma together with the key histopathologic features and highlights of the previously reported cases.

摘要

自然杀伤/T细胞淋巴瘤是一种罕见的、与EB病毒相关的细胞毒性淋巴瘤,主要发生在鼻腔及其附近。迄今为止,原发性皮肤结外自然杀伤/T细胞淋巴瘤的病例报道极少。所有先前报道的原发性皮肤结外自然杀伤/T细胞淋巴瘤病例均表现为类似蜂窝织炎、皮下结节或溃疡的病变。我们报告一例罕见病例,该病例表现为手臂上的红斑和紫癜性圆形斑块,经皮肤活检最终诊断为原发性皮肤结外自然杀伤/T细胞淋巴瘤。这些非典型斑块样病变带来了诊断挑战。我们在此描述原发性皮肤结外自然杀伤/T细胞淋巴瘤这种临床上新颖的非典型斑块样表现,以及关键的组织病理学特征和先前报道病例的要点。

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