Singh Abhijeet, Gupta Ayush, Suri Jagdish Chander
Department of Pulmonary, Critical Care and Sleep Medicine, VMMC and Safdarjung Hospital, New Delhi, India.
Lung India. 2017 May-Jun;34(3):269-272. doi: 10.4103/lungindia.lungindia_386_16.
A case of 60-year-old male with acute pulmonary embolism without hypotension but signs of right ventricular dysfunction and elevated cardiac biomarkers is reported in this study. The patient comes under intermediate high-risk category and was successfully thrombolysed with alteplase infused through pulmonary artery catheter. Catheter-directed thrombolysis (CDT) can be considered as much safer and effective alternative to systemic thrombolysis in such patients with lower risk of bleeding. This novel bedside method of pulmonary artery CDT with the advantage of no radiation exposure and real time monitoring of pulmonary artery pressures as an end-point of thrombolysis can be utilized in the near future.
本研究报告了一例60岁男性急性肺栓塞患者，该患者无低血压，但有右心室功能障碍体征且心脏生物标志物升高。该患者属于中高危类别，通过肺动脉导管注入阿替普酶成功进行了溶栓治疗。对于此类出血风险较低的患者，导管定向溶栓（CDT）可被视为比全身溶栓更安全有效的替代方法。这种新型的床边肺动脉CDT方法具有无辐射暴露以及实时监测肺动脉压力作为溶栓终点的优点，在不久的将来可能会得到应用。
