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糖尿病足溃疡患者足部手术后的结局及12个月随访

Outcomes after foot surgery in people with a diabetic foot ulcer and a 12-month follow-up.

作者信息

Lenselink E, Holloway S, Eefting D

机构信息

Wound Expert Clinic, Haaglanden Medical Centre, The Hague, The Netherlands.

Senior Lecturer, Centre for Medical Education, Cardiff University School of Medicine, College of Biomedical and Life Sciences, Cardiff, Wales, UK.

出版信息

J Wound Care. 2017 May 2;26(5):218-227. doi: 10.12968/jowc.2017.26.5.218.

DOI:10.12968/jowc.2017.26.5.218
PMID:28475445
Abstract

OBJECTIVE

The aim of this study was to retrospectively measure the outcomes of foot-sparing surgery at one year follow-up for patients with diabetic foot ulcers (DFUs). We assessed wound healing and the need for further surgery in relation to the variables that influence healing.

METHOD

Data were retrospectively collected by reviewing the electronic files of patients attending the Wound Expert Clinic (WEC). Outcomes of surgical debridement, toe, ray and transmetatarsal amputations were assessed.

RESULTS

A total of 129 cases in 121 patients were identified for inclusion. The results demonstrated that complete wound healing was reached in 52% (61/117) of the patients within 12 months. The need for additional surgery or for major amputation was 56% (n=72/129) and 30% (n=39/129) respectively. The need for an additional procedure was particularly high after surgical debridement (75%, 33/44) and transmetatarsal amputation (64%, 7/11). Risk factors for non-healing or for a major amputation were: infection (p=0.01), ischaemia (p=0.01), a history of peripheral arterial occlusive disease (p<0.01) and smoking (p=0.01). Additional findings were that not all patients underwent vascular assessment and in half of the patients there was a delay in undergoing revascularisation.

CONCLUSION

The results of the study reveal some areas for improvement including timely revascularisation and performance of multiple debridement procedures if needed in order to save a limb.

摘要

目的

本研究的目的是回顾性评估糖尿病足溃疡(DFU)患者足部保留手术一年随访的结果。我们评估了伤口愈合情况以及与影响愈合的变量相关的进一步手术需求。

方法

通过查阅伤口专家诊所(WEC)就诊患者的电子病历,回顾性收集数据。评估手术清创、趾部、射线和经跖骨截肢的结果。

结果

共纳入121例患者的129例病例。结果显示,52%(61/117)的患者在12个月内实现了完全伤口愈合。额外手术或大截肢的需求分别为56%(n=72/129)和30%(n=39/129)。手术清创(75%,33/44)和经跖骨截肢(64%,7/11)后额外手术的需求尤其高。不愈合或大截肢的危险因素为:感染(p=0.01)、缺血(p=0.01)、外周动脉闭塞性疾病史(p<0.01)和吸烟(p=0.01)。其他发现包括并非所有患者都接受了血管评估,且一半患者在进行血运重建时存在延迟。

结论

研究结果揭示了一些需要改进的方面,包括及时进行血运重建以及在必要时进行多次清创手术以挽救肢体。

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