Departments of Biosciences and Bioengineering, Rice University, Houston, TX 77005, USA.
Cell Stem Cell. 2017 May 4;20(5):581-582. doi: 10.1016/j.stem.2017.04.001.
Mammalian embryonic stem cells (ESCs) can self-organize in vitro, but whether they can recreate early embryonic morphogenesis is unclear. Harrison et al. recently demonstrate in Science that 3D co-cultures of mouse ESCs and trophoblast stem cells self-organize into embryo-like structures that recreate many features of early mouse development.
哺乳动物胚胎干细胞（ESCs）可以在体外自我组织，但它们是否能够重现早期胚胎形态发生尚不清楚。Harrison 等人最近在《科学》杂志上表明，将小鼠 ESCs 和滋养层干细胞的 3D 共培养物自组织成类似胚胎的结构，重现了早期小鼠发育的许多特征。
