Akhtar Azeem, Hussain Ijaz, Talha Muhammad, Shakeel Muhammad, Faisal Muhammad, Ameen Muhammad, Hussain Tajammal
College of Statistical and Actuarial Sciences, University of Punjab, Lahore, Pakistan.
Department of Statistics, Quaid-i-Azam University, Islamabad, Pakistan.
Pak J Pharm Sci. 2016 Sep;29(5 Suppl):1839-1846.
Head and Neck (HN) cancer is the most frequently identified cancer across the globe and is considered as 8-10 % of all cancers in Southeast Asia. The social and cultural habits are the main cause of the remarkable increase in HN cancer in Pakistan. HN cancers are more prevalent in men as compared to women. The HN cancer in Pakistan is mainly attributed to discrete demographic profile, risk elements, eating patterns and family history. The foremost factors of risk are linked with cigarette smoking, alcoholic drinks and tobacco chewing like paan, gutka, etc. The actual burden of HN cancer in Pakistan is 18.74% of all new cancer cases recorded during 2004 -2014. The data is collected from HN cancer patients who are diagnosed from September 2011 till May 2012 in the Institute of Nuclear medicine and Oncology, Lahore Pakistan. In order to diagnose risk factors of HN cancer, the Logistic Regression (LR) and Linear Discriminant Analysis (LDA) are used as analytical tools. The findings of using these both tools concluded that gender, age, occupation, socioeconomic status, family history, chewing habits, smoking habit, worked in the chemical or dust place, alcohol use are main causes for HN cancer. The main aim of this study is to develop the awareness about HN cancer, its causes and early diagnosis.
头颈癌是全球最常见的癌症,在东南亚占所有癌症的8%至10%。社会和文化习惯是巴基斯坦头颈癌显著增加的主要原因。与女性相比,头颈癌在男性中更为普遍。巴基斯坦的头颈癌主要归因于不同的人口统计学特征、风险因素、饮食习惯和家族病史。主要的风险因素与吸烟、饮酒以及嚼食槟榔、古特卡等烟草有关。2004年至2014年期间,巴基斯坦头颈癌实际负担占所有新确诊癌症病例的18.74%。数据收集自2011年9月至2012年5月在巴基斯坦拉合尔核医学与肿瘤研究所确诊的头颈癌患者。为了诊断头颈癌的风险因素,采用逻辑回归(LR)和线性判别分析(LDA)作为分析工具。使用这两种工具的结果表明,性别、年龄、职业、社会经济地位、家族病史、咀嚼习惯、吸烟习惯、在化学或粉尘环境中工作、饮酒是头颈癌的主要病因。本研究的主要目的是提高对头颈癌及其病因和早期诊断的认识。