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日常生活认知工具性活动的两种测量方法之间的关联及其与中风患者蒙特利尔认知评估的关系

Association Between 2 Measures of Cognitive Instrumental Activities of Daily Living and Their Relation to the Montreal Cognitive Assessment in Persons With Stroke.

作者信息

Toglia Joan, Askin Gulce, Gerber Linda M, Taub Michael C, Mastrogiovanni Andrea R, O'Dell Michael W

机构信息

School of Health and Natural Sciences, Mercy College, Dobbs Ferry, NY; Department of Rehabilitation Medicine, NewYork-Presbyterian/Weill Cornell Medical Center, New York, NY.

Department of Healthcare Policy & Research, Weill Cornell Medical College, New York, NY.

出版信息

Arch Phys Med Rehabil. 2017 Nov;98(11):2280-2287. doi: 10.1016/j.apmr.2017.04.007. Epub 2017 May 4.

Abstract

OBJECTIVES

To explore the relation between a computer adaptive functional cognitive questionnaire and a performance-based measure of cognitive instrumental activities of daily living (C-IADL) and to determine whether the Montreal Cognitive Assessment (MoCA) at admission can identify those with C-IADL difficulties at discharge.

DESIGN

Prospective cohort study.

SETTING

Acute inpatient rehabilitation unit of an academic medical center.

PARTICIPANTS

Inpatients (N=148) with a diagnosis of stroke (mean age, 68y; median, 13d poststroke) who had mild cognitive and neurological deficits.

INTERVENTIONS

Not applicable.

MAIN OUTCOME MEASURES

Admission cognitive status was assessed by the MoCA. C-IADL at discharge was assessed by the Executive Function Performance Test (EFPT) bill paying task and Activity Measure of Post-Acute Care (AM-PAC) Applied Cognition scale.

RESULTS

Greater cognitive impairment on the MoCA was associated with more assistance on the EFPT bill paying task (ρ=-.63; P<.01) and AM-PAC Applied Cognition scale (ρ=-.43; P<.01). This relation was nonsignificant for higher MoCA scores and EFPT bill paying task scores. The AM-PAC Applied Cognition scale and the EFPT bill paying task had low agreement in classifying functional performance (Cohen's κ=.20). A receiver operating characteristic curve identified optimal MoCA cutoff scores of 20 and 21 for classifying EFPT bill paying task status and AM-PAC Applied Cognition scale status, respectively. For values above 20 and 21, sensitivity increased whereas specificity decreased for classifying functional deficits. Approximately one third of the participants demonstrated C-IADL deficits on at least 1 C-IADL measure at discharge despite having a MoCA score of ≥26 at admission.

CONCLUSIONS

Questionnaire and performance-based methods of assessment appear to yield different estimates of C-IADL. Low MoCA scores (<20) are more likely to identify those with C-IADL deficits on the EFPT bill paying task. The results suggest that C-IADL should be assessed in those who have mild or no cognitive difficulties at admission.

摘要

目的

探讨计算机自适应功能认知问卷与基于表现的日常生活认知工具性活动(C-IADL)测量之间的关系,并确定入院时的蒙特利尔认知评估(MoCA)是否能够识别出院时存在C-IADL困难的患者。

设计

前瞻性队列研究。

地点

一所学术医疗中心的急性住院康复单元。

参与者

148名诊断为中风的住院患者(平均年龄68岁;中风后中位数为13天),他们有轻度认知和神经功能缺损。

干预措施

不适用。

主要结局指标

入院时的认知状态通过MoCA进行评估。出院时的C-IADL通过执行功能表现测试(EFPT)支付账单任务和急性后期护理活动测量(AM-PAC)应用认知量表进行评估。

结果

MoCA上更严重的认知障碍与EFPT支付账单任务(ρ = -0.63;P <.01)和AM-PAC应用认知量表(ρ = -0.43;P <.01)上需要更多帮助相关。对于较高的MoCA分数和EFPT支付账单任务分数,这种关系不显著。AM-PAC应用认知量表和EFPT支付账单任务在功能表现分类上的一致性较低(Cohen's κ = 0.20)。一条受试者工作特征曲线确定了分别用于分类EFPT支付账单任务状态和AM-PAC应用认知量表状态的最佳MoCA截止分数为20和21。对于高于20和21的值,在分类功能缺损时敏感性增加而特异性降低。尽管入院时MoCA分数≥26,但约三分之一的参与者在出院时至少在一项C-IADL测量上表现出C-IADL缺损。

结论

问卷和基于表现的评估方法似乎对C-IADL产生不同的估计。低MoCA分数(<20)更有可能识别出在EFPT支付账单任务上存在C-IADL缺损的患者。结果表明,对于入院时轻度认知困难或无认知困难的患者,应评估其C-IADL。

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