Horcholle-Bossavit G, Jami L, Lafleur J, Lamy F, Zytnicki D
Laboratoire de Neurophysiologie, Collège de France, Paris.
C R Acad Sci III. 1988;307(10):591-6.
Autogenetic inhibition of homonymous and synergist motoneurones can be elicited by very weak partial twitches of gastrocnemius medialis muscle, but during sustained contractions the amplitude of inhibitory post-synaptic potentials decreases quickly. A similar decrease also occurs during stronger contractions. The mechanism responsible for this decrease is still active in low spinal preparations. Pre-synaptic inhibition of Ib afferent fibres might contribute to this reduction of efficiency in the transmission of Ib afferent inputs to motoneurones.
腓肠肌内侧肌非常微弱的局部抽搐可引发同名和协同运动神经元的自生抑制,但在持续收缩过程中,抑制性突触后电位的幅度会迅速降低。在更强的收缩过程中也会出现类似的降低。这种降低的机制在低位脊髓标本中仍然起作用。Ib传入纤维的突触前抑制可能导致Ib传入输入向运动神经元传递的效率降低。