Welsh D M, Zumwalt C B
St. Luke's Hospital, Chesterfield, MO 63017.
J Neurosci Nurs. 1988 Aug;20(4):229-35. doi: 10.1097/01376517-198808000-00005.
Malignant glioma is a devastating disease which presents a clinical challenge to physicians and neuroscience nurses. It carries a dismal prognosis, with a median survival of only nine months following application of conventional therapies of surgical resection, radiotherapy and chemotherapy. Hyperthermia is the application of sufficient heat to raise the temperature in a volume of tumor to cytocidal levels. Patient tolerance and response to volumetric interstitial hyperthermia treatment in this clinical study of over 40 patients has been extremely encouraging. Hyperthermia, as part of multi-modality treatment of brain tumors, presents a change in the nursing management of this patient population. The neuroscience nurse plays a crucial role in linking clinical observations to decisions of patient management and treatment planning. Because hyperthermia is a new treatment modality, nurses, patients and families require additional education and extended support during therapy.
恶性胶质瘤是一种极具毁灭性的疾病,给医生和神经科学护士带来了临床挑战。其预后很差,采用手术切除、放疗和化疗等传统疗法后,中位生存期仅为9个月。热疗是指施加足够的热量,使一定体积肿瘤内的温度升高到杀灭细胞的水平。在这项针对40多名患者的临床研究中,患者对容积性组织间热疗治疗的耐受性和反应非常令人鼓舞。热疗作为脑肿瘤多模式治疗的一部分,给这类患者的护理管理带来了变化。神经科学护士在将临床观察结果与患者管理和治疗计划的决策联系起来方面起着至关重要的作用。由于热疗是一种新的治疗方式,在治疗期间,护士、患者和家属需要额外的教育和更多的支持。