Martin F M, Hamilton W, Dons R, Cashell A W, Ghosh B C
Department of Surgery, Naval Hospital, Bethesda, MD 20814.
J Surg Oncol. 1988 Dec;39(4):256-9. doi: 10.1002/jso.2930390408.
A case is described that represents the only reported patient with glucagonoma syndrome and morbid obesity. The diagnosis of glucagonoma should be considered in any patient with the classic criteria despite weight gain. The criteria for diagnosis of glucagonoma are 1) the presence of a glucagon-secreting tumor, 2) hyperglucagonemia, and 3) the clinical manifestations of either necrolytic migratory erythema, glucose intolerance, or hypoaminoacidemia.
本文描述了一例报告的唯一同时患有胰高血糖素瘤综合征和病态肥胖症的患者。尽管体重增加，但对于任何符合经典标准的患者都应考虑胰高血糖素瘤的诊断。胰高血糖素瘤的诊断标准为：1）存在分泌胰高血糖素的肿瘤；2）高胰高血糖素血症；3）坏死性游走性红斑、葡萄糖不耐受或低氨基酸血症的临床表现。
